Document And Entity Information [Abstract] Document Information [Table] Class of Stock [Axis] Statement of Financial Position [Abstract] Statement [Table] Class of Stock [Domain] Statement [Line Items] Assets, Current [Abstract] Current Assets Cash and Cash Equivalents, at Carrying Value, Total Cash and cash equivalents Checking and savings accounts (reported as cash and cash equivalents) Cash and Cash Equivalents, Beginning of Period Cash and Cash Equivalents, End of Period Cash and Cash Equivalents, at Carrying Value Available-for-sale Securities, Current, Total Short-term investments Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Assets, Current, Total Total Current Assets Property, Plant and Equipment, Net, Total Property and equipment, net Property and equipment, net Assets, Total Total Assets Liabilities, Current [Abstract] Current Liabilities Accounts Payable, Current Accounts payable Accrued Liabilities, Current Accrued expenses Accrued Liabilities, Current Liabilities, Current, Total Total Current Liabilities Commitments and Contingencies Commitments and contingencies (see note 11) Preferred Stock, Value, Issued Preferred stock,Value Common Stock, Value, Issued Common stock, $0.000041666 par value; 150,000,000 shares authorized, 62,248,074 and 48,547,720 shares issued and outstanding as of December 31, 2016 and 2015, respectively Additional Paid in Capital, Total Additional paid-in capital Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accumulated other comprehensive income Retained Earnings (Accumulated Deficit), Total Accumulated deficit Stockholders' Equity Attributable to Parent, Total Total Stockholders’ Equity Beginning Balance Ending Balance Liabilities and Equity, Total Total Liabilities and Stockholders’ Equity Income Statement [Abstract] Revenues, Total Revenues Revenue Research and Development Expense, Total Research and development General and Administrative Expense, Total General and administrative Operating Expenses [Abstract] Costs and expenses Operating Income (Loss), Total Loss from operations Investment Income, Interest Interest income Nonoperating Income (Expense) [Abstract] Other income Other Preferred Stock Dividends and Adjustments Deemed dividend related to beneficial conversion feature of convertible preferred stock Statement of Comprehensive Income [Abstract] Net Income (Loss) Attributable to Parent, Total Net Loss Net Loss Net loss attributable to common stockholders Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Other comprehensive income: Other Comprehensive Income (Loss), Unrealized Holding Gain (Loss) on Securities Arising During Period, Net of Tax Unrealized (loss) gain on short-term investments Unrealized loss on short- term investments Comprehensive Income (Loss), Net of Tax, Attributable to Parent, Total Comprehensive Loss Stockholders' Equity Attributable to Parent [Abstract] Stockholders' Equity Equity Components [Axis] Statement of Cash Flows [Abstract] Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Cash Flows From Operating Activities Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Depreciation, Depletion and Amortization, Nonproduction, Total Depreciation and amortization Amortization of Debt Discount (Premium) Amortization of premium on investments Increase (Decrease) in Operating Capital [Abstract] Changes in assets and liabilities: Increase (Decrease) in Prepaid Expense and Other Assets, Total Prepaid expenses and other current assets Net Cash Provided by (Used in) Operating Activities, Continuing Operations, Total Net cash used in operating activities Share-based Compensation Stock-based compensation expense Payments to Acquire Available-for-sale Securities, Total Purchase of short- term investments Proceeds from Sale and Maturity of Available-for-sale Securities, Total Maturities of short- term investments Payments to Acquire Property, Plant, and Equipment, Total Purchase of property and equipment Net Cash Provided by (Used in) Investing Activities, Continuing Operations, Total Net cash provided by (used in) investing activities Increase (Decrease) in Accounts Payable Accounts payable Payments Related to Tax Withholding for Share-based Compensation Tax payments related to shares witheld for vested restricted stock awards Proceeds from Warrant Exercises Proceeds from the issuance of common stock upon exercise of warrants Proceeds from Stock Options Exercised Proceeds from the issuance of common stock upon exercise of options Proceeds from Issuance of Common Stock Proceeds from the issuance of preferred stock and common stock, net Increase (Decrease) in Accrued Liabilities Accrued expenses Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Cash Flows From Investing Activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Cash Flows From Financing Activities Cash and Cash Equivalents, Period Increase (Decrease), Total Net increase(decrease) in cash and cash equivalents Other Significant Noncash Transaction, Value of Consideration Received Unrealized (loss)gain on short-term investments Equity Component [Domain] Common Stock [Member] Common Stock To Be Issued [Member] Common Stock to be Issued [Member] Additional Paid-in Capital [Member] AOCI Attributable to Parent [Member] Comprehensive Income [Member] Retained Earnings [Member] Accumulated Deficit [Member] Shares, Outstanding, Beginning Balance Beginning Balance (in Shares) Ending Balance (in Shares) Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Stock-based compensation expense Adjustment to Additional Paid in Capital, Income Tax Effect from Share-based Compensation, Net Tax payments related to shares witheld for vested restricted stock awards Common Stock Issued Upon Exercise Of Warrants Amount Common stock issued upon exercise of warrants The amount of exchange transaction inducement costs capitalized during the period. Common Stock Issued Upon Exercise Of Warrants Shares Common stock issued upon exercise of warrants (in Shares) Number of shares issued upon exercise of warrant. Stock Issued During Period, Value, Stock Options Exercised Common stock issued upon exercise of stock options Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Common stock issued upon exercise of stock options (in shares) Exercised Stock Issued During Period, Value, Issued for Services Common stock issued for services Stock Issued During Period, Shares, Issued for Services Common stock issued for services (in shares) Stock Issued During Period, Value, New Issues Common stock sold in public offering, net of offering costs Stock Issued During Period, Shares, New Issues Common stock sold in public offering, net of offering costs (in shares) Stock Issued During Period, Value, Other Common stock sold in private placement, net of offering costs Stock Issued During Period, Shares, Other Common stock sold in private placement, net of offering costs (in shares) PreferredStockSoldInPrivatePlacementValue Preferred stock sold in private placement, net of offering costs Value of preferred stock sold in private placement net of offering costs. Preferred Stock Sold In Private Placement Shares Preferred stock sold in private placement, net of offering costs (in shares) Number of shares of preferred stock sold in private placement net of offering costs. Preferred Stock, Par or Stated Value Per Share Preferred Stock, Shares Authorized Preferred Stock, Shares Issued Preferred Stock, Shares Outstanding Common Stock, Par or Stated Value Per Share Common Stock, Shares Authorized Common Stock, Shares, Issued Common Stock, Shares, Outstanding Organization, Consolidation and Presentation of Financial Statements [Abstract] Business Description and Basis of Presentation [Text Block] GENERAL ORGANIZATION, BUSINESS AND LIQUIDITY Cash, Cash Equivalents, and Short-term Investments, Total Total Accounting Policies [Abstract] Significant Accounting Policies [Text Block] SUMMARY OF SIGNIFICANT ACCOUNTING PRACTICES Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Marketable Securities, Policy [Policy Text Block] Short-term Investments Property, Plant and Equipment, Policy [Policy Text Block] Property and Equipment Fair Value Measurement, Policy [Policy Text Block] Fair value of financial instruments Earnings Per Share, Policy [Policy Text Block] Loss per Share Fair Value of Financial Instruments, Policy [Policy Text Block] Fair Value Measurements Use of Estimates, Policy [Policy Text Block] Use of Estimates Share-based Compensation, Option and Incentive Plans Policy [Policy Text Block] Stock-Based Compensation Research and Development Expense, Policy [Policy Text Block] Research and Development Selling, General and Administrative Expenses, Policy [Policy Text Block] General and Administrative Expenses Income Tax, Policy [Policy Text Block] Income taxes Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentrations Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share Fair Value, Assets Measured on Recurring Basis [Table Text Block] Schedule of Assets Measured at Fair Value Measurement Frequency [Axis] Assets, Fair Value Disclosure, Total Fair Value, Hierarchy [Axis] Fair Value, Measurement Frequency [Domain] Cash and Cash Equivalents [Axis] Fair Value Hierarchy [Domain] Fair Value, Inputs, Level 1 [Member] Major Types of Debt and Equity Securities [Axis] Cash and Cash Equivalents [Domain] Major Types of Debt and Equity Securities [Domain] Corporate Debt Securities [Member] Fair Value, Inputs, Level 2 [Member] Fair Value, Inputs, Level 3 [Member] Income Statement Location [Axis] Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost, Total Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost, Total Income Statement Location [Domain] Research and Development Expense [Member] Research and Development Expense [Member] Derivative Instrument [Axis] Antidilutive Securities [Axis] Derivative Contract [Domain] Award Type [Axis] Antidilutive Securities, Name [Domain] Customer [Axis] Equity Award [Domain] Concentration Risk Benchmark [Axis] Customer [Domain] Range [Axis] Concentration Risk Benchmark [Domain] Property, Plant and Equipment, Useful Life Property, Plant and Equipment, Type [Axis] Range [Domain] Maximum [Member] Minimum [Member] Cash, Cash Equivalents, and Short-term Investments [Abstract] Cash, Cash Equivalents, and Short-term Investments [Text Block] Cash, Cash Equivalents and Investments [Table Text Block] Schedule of Cash, Money Market Funds and Short-Term Investments Unrealized Gain (Loss) on Investments [Table Text Block] Schedule of Unrealized Gains and Losses Investments Classified by Contractual Maturity Date [Table Text Block] Schedule of Contractual Maturities Trading Securities, Cost Amortized Cost Money Market Funds [Member] Trading Securities, Unrealized Holding Gain Gross Unrealized Gains Trading Securities, Unrealized Holding Loss Gross Unrealized Losses Investment Owned, at Fair Value Fair Value Loss Contingency [Abstract] Contingencies Disclosure [Text Block] LEGAL PROCEEDINGS Related Party [Axis] Loss Contingency, Damages Sought, Value Commitments and Contingencies Disclosure [Abstract] Other Commitments [Table] License And Commitments [Table] Lease Arrangement, Type [Axis] Supplemental Balance Sheet Disclosures [Text Block] PROPERTY AND EQUIPMENT Property, Plant and Equipment [Abstract] Property, Plant and Equipment [Table Text Block] Schedule of Property, Plant and Equipment Property, Plant and Equipment, Gross, Total Total Property and equipment, cost Property, Plant and Equipment, Type [Domain] Equipment [Member] Lab Equipment [Member] Computer Equipment [Member] Office Equipment [Member] Office Furniture and Equipment [Member] Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Less: Accumulated depreciation and amortization Depreciation, Total Stockholders' Equity Note [Abstract] Stockholders' Equity Note Disclosure [Text Block] STOCKHOLDERS’ EQUITY Schedule of Stock by Class [Table] Series A Convertible Preferred Stock [Member] Class of Stock [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Number of Shares Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number, Beginning Balance Non-vested shares, Beginning Balance Non-vested shares, Ending Balance Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period Granted Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period Vested Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Weighted Average Grant Date Fair Value Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value, Beginning Balance Weighted Average Grant Date Fair Value, Beginning Balance Weighted Average Grant Date Fair Value, Ending Balance Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Granted Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Vested Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Forfeited Conversion of Stock, Shares Issued Conversion of Stock, Shares Converted Creditor [Axis] Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Text Block] STOCK OPTIONS AND WARRANTS Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Schedule of Status of Stock Options Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Number of Options Shares Under Warrants Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number, Beginning Balance Outstanding, beginning balance Outstanding, ending balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Granted Issued Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period Expired/Forfeited Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Vested and Expected to Vest Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract] Weighted Average Exercise Price Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Beginning Balance Outstanding, beginning balance Outstanding, ending balance Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Granted Issued Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Exercised Exercised Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price Expired/Forfeited ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosures [Abstract] Weighted Average Remaining Contractual Life Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Outstanding AggregateIntrinsicValue [Abstract] Aggregate Intrinsic Value Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Outstanding, beginning balance Outstanding, ending balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value Exercisable Equity-Based Arrangements, Individual Contracts, Type of Deferred Compensation [Axis] Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized Allocated Share-based Compensation Expense Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Total Plan Name [Axis] Equity-Based Arrangements, Individual Contracts, Type of Deferred Compensation [Domain] Plan Name [Domain] Plan Two [Member] 2014 [Member] Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Exercisable Shares Issued Plan [Axis] Option Indexed to Issuer's Equity, Type [Axis] Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period Forfeited Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Option Indexed to Issuer's Equity, Type [Domain] Employee Stock Option [Member] General and Administrative Expense [Member] Net Income (Loss) Available to Common Stockholders, Basic, Total Net Loss Attributable to common Stockholders Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Schedule of Stock-Based Compensation Earnings Per Share, Basic and Diluted, Total Net Loss Per Common Share, Basic and Diluted Net loss per share, basic and diluted Weighted Average Number of Shares Outstanding, Basic and Diluted Weighted-Average Common Shares Outstanding, Basic and Diluted Weighted average shares used in computing net loss per share, basic and diluted Stock Issued During Period, Value, Conversion of Convertible Securities Conversion of convertible preferred stock into common stock Stock Issued During Period, Shares, Conversion of Convertible Securities Conversion of convertible preferred stock into common stock (in Shares) Stockholders' Equity Note, Redeemable Preferred Stock, Issue, Policy [Policy Text Block] Preferred Stock Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] INCOME TAXES Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Schedule of Deferred Tax Assets and Liabilities Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Schedule of Effective Income Tax Rate Reconciliation Operating Expenses, Total Total costs and expenses Stock Cancelled During Period Restricted Shares Value Cancellation of restricted shares The value of restricted shares cancelled during the period. Stock Cancelled During Period Restricted Shares Cancellation of restricted shares (in Shares) The number of restricted shares cancelled during the period. Adjustments To Additional Paid In Capital Preferred Stock With Conversion Feature Beneficial conversion feature of preferred stock Amount of increase (decrease) in additional paid in capital (APIC) resulting from preferred stock with a beneficial conversion feature. Adjustments to Additional Paid in Capital, Other Deemed dividend on beneficial conversion feature of preferred stock Convertible Instruments Policy [Text Block] Convertible Instruments The accounting policy for all convertible instruments issued by the entity. Leasehold Improvements [Member] Sale of Stock, Price Per Share Troubled Debt Restructuring, Debtor, Current Period, Creditor [Domain] Sale of Stock [Axis] Related Party [Domain] Sale of Stock [Domain] Private Placement [Member] Stock Conversion Description [Axis] Title of Individual [Axis] Conversion of Stock, Name [Domain] Issuance Of Common Stock Upon Conversion Of Preferred Stock [Member] Convertible Price Per Shares The price per share at which the preferred stock of an entity is converted. Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Vested and Expected to Vest Deferred Tax Assets, Operating Loss Carryforwards, Total Net operating loss carry forward Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-based Compensation Cost Stock-based compensation Deferred Tax Assets, Tax Credit Carryforwards Tax credit carryforwards Deferred Tax Assets, Net [Abstract] Deferred income tax asset: Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Federal Statutory tax rate Effective Income Tax Rate Reconciliation, Tax Credit, Percent Orphan Drug & Research credits Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate, Percent Permanent and Other differences Effective Income Tax Rate Reconciliation, Tax Settlement, State and Local, Percent State tax, net of federal benefit EffectiveIncomeTaxRateReconciliationExpectedRateTotal1 Effective Income Tax Rate Reconciliation Expected Rate Total Represents the sum of Federal Statutory tax rate and State tax net of federal benefit. Income Tax Contingency [Table] Income Tax Authority [Axis] Area of Land Operating Leases, Rent Expense Indefinite-lived Intangible Assets [Axis] Lease Arrangement, Type [Domain] Tampa Lease [Member] Other Commitments [Line Items] License And Commitments [Line Items] Indefinite-lived Intangible Assets, Major Class Name [Domain] Relationship to Entity [Domain] Shares Issued Plan [Domain] Document Type Amendment Flag Document Period End Date Document Fiscal Year Focus Document Fiscal Period Focus Entity Registrant Name Entity Central Index Key Current Fiscal Year End Date Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Current Reporting Status Entity Filer Category Entity Public Float Trading Symbol Entity Common Stock, Shares Outstanding Lease Expiration Term Expiration term of the lease agreement. Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Table Text Block] Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan Series B Preferred Stock [Member] Series A Preferred Stock [Member] Preferred Stock, Redemption Amount Net Cash Provided by (Used in) Financing Activities, Continuing Operations, Total Net cash provided by financing activities Supplemental Cash Flow Information [Abstract] Supplemental Disclosures of Cash Flow Information: Deemed Dividend Related To Beneficial Conversion Feature Deemed dividend related to a beneficial conversion feature Amount of deemed dividend related to beneficial conversion feature. Conversion of Stock, Amount Converted Conversion of convertible preferred stock to common stock Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental disclosure of non-cash investing and financing activities: Income Taxes Paid, Net Cash paid for income taxes Interest Paid, Net Interest paid Subsequent Events [Abstract] Subsequent Events [Text Block] Related Party Transactions [Abstract] Related Party Transactions Disclosure [Text Block] Payments for Legal Services The amount of cash paid for the legal service during the period. Due to Related Parties, Current Quarterly Financial Information Disclosure [Abstract] Quarterly Financial Information [Text Block] Quarterly Financial Information [Table Text Block] Quarterly Financial Information Securities or Other Assets Sold under Agreements to Repurchase [Axis] Solomon Capital, LLC [Member] Proceeds from Related Party Debt Debt Instrument, Face Amount Debt Instrument, Convertible, Number of Equity Instruments Loss Contingency, Estimate of Possible Loss Assets Sold under Agreements to Repurchase, Type [Domain] Commercial Paper [Member] Stockholders' Equity, Reverse Stock Split Warrant [Member] Restricted Stock Awards [Member] Restricted Stock [Member] Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount US Government Debt Securities [Member] US Government agency securities [Member] Available-for-sale Securities Corporate debt securities (reported as short-term investments) Corporate debt securities Available-for-sale Securities Investment Type [Axis] Demand Deposits [Member] Compensation and Retirement Disclosure [Abstract] Compensation and Employee Benefit Plans [Text Block] Investments [Domain] Defined Contribution Plan, Cost Recognized Restructuring and Related Activities [Abstract] Separation Agreements Disclosure [Text Block] The entire disclosure for separation agreements. Dr. Elma Hawkins [Member] Molly Henderson [Member] Severance Costs Share-based Compensation Arrangement by Share-based Payment Award Accelerated Compensation Cost Available-for-sale Securities, Amortized Cost Basis Sock Issued During Period Preferred Stock Shares Number of prefereed stock issued during the period. Includes preferred shares issued in an initial public offering or a secondary public offering. Commitments and Contingencies Disclosure [Text Block] LICENSES AND COMMITMENTS Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block] Schedule of Future Minimum Rental Payments for Operating Leases Operating Leases, Future Minimum Payments Due, Next Twelve Months 2017 2017 Operating Leases, Future Minimum Payments, Due in Two Years 2018 2018 Operating Leases, Future Minimum Payments, Due in Three Years 2019 2019 Operating Leases, Future Minimum Payments, Due in Four Years 2020 2020 Operating Leases, Future Minimum Payments, Due in Five Years 2021 2021 Operating Leases, Future Minimum Payments Due Total New York Lease [Member] Operating Leases, Rent Expense, Minimum Rentals Purchase Obligation Licenses And Agreements [Abstract] Licenses And Agreements Disclosure [Text Block] The entire disclosure for licenses and agreements. Finite-Lived Intangible Assets by Major Class [Axis] Legal Entity [Axis] Finite-Lived Intangible Assets, Major Class Name [Domain] Exclusive Patent License Agreement [Member] Moffitt License Agreement [Member] Entity [Domain] KarolinskaUniversityHospital [Member] Payments For Upfront Licensing Fee This element represents the amount of cash outflow for the payment of upfront licensing fee. Payments For Clinical Trials Agreement This element represents the amount of cash outflow for the payment of clinical trails agreement. Payment For Upfront Exclusive License Amount paid for un-front licence agreement. Additional Milesone Payable Additional Milesone Payable Additional amount of milestone have to be made. Number Of Unregistered Common Stock To Be Issued Number Of Unregistered Common Stock To Be Issued Number of unregistered common stock to be issued. ReimbursementIn Relation To Transfer Of Knowhow ReimbursementIn Relation To Transfer Of Knowhow Amount of reimbursement will be made in relation to transfer of know-how. Clinical Trials Management Fees Payable Amount of clinical tials management fees payable. Consulting Fees Receivable Amount of consulting fees for sevices rendered related to poduct development and research will be receivable. Initial Term Of Licence Agreement It represents for initial term of licence agreement. Repayments To Be Made For Termination Of Licence Agreement Amount of repayment which will be made for the temination of licence agreement. Payments To Be Made For Other Related Agreements Amount of payment which will be made for other related agreement. Common Stock Registered For Resale Number of common shares which registered for resale. Shares Sold Under Ineffective Registration The number of shares that may be sale by the shareholders under ineffectiveregistration statement. Number of share options or share units exercised during the current period. Number of share options (or share units) exercised during the current period. Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] Schedule of Status of Stock Warrants Series B Convertible Preferred Stock [Member] Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period Expired/Forfeited Share-based Compensation Arrangements by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Expired Expired/Cancelled Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding and Exercisable [Table Text Block] Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding and Exercisable Schedule of Nonvested Restricted Stock Units Activity [Table Text Block] Schedule of Nonvested Restricted Stock Units Activity Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk-free interest rate Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Expected term (in years) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate Expected volatility Exercise Price Range [Axis] Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Domain] Range Of Exercise Prices One [Member] Range Of Exercise Prices $3.13 - $4.94 [Member] Range Of Exercise Prices Two [Member] Range Of Exercise Prices $5.05 - $5.87 [Member] Range Of Exercise Prices Three [Member] Range Of Exercise Prices $6.10 - $6.70 [Member] Range Of Exercise Prices Four [Member] Range Of Exercise Prices $7.00 - $7.61 [Member] Range Of Exercise Prices Five [Member] Range Of Exercise Prices $8.02 - $11.05 [Member] Range Of Exercise Prices Six [Member] Range Of Exercise Prices $85.61 - $117 [Member] Equity Incentive Plan [Member] 2014 Equity Incentive Plan [Member] Restricted Common Stock [Member] Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value Proceeds from Issuance of Private Placement Two Thousand And Sixteen Private Placement [Member] 2016 Private Placement [Member] Shares Issued, Price Per Share Proceeds from Issuance or Sale of Equity Schedule of Accrued Liabilities [Table Text Block] Schedule of Accrued Liabilities Construction in Progress [Member] Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals Reserves and accruals Deferred Tax Assets, Gross Deferred tax asssets before valuation allowance Deferred Tax Assets, Valuation Allowance Less: valuation allowance Deferred Tax Assets, Net of Valuation Allowance, Total Net deferred income tax assets Accrued Employee Benefits, Current Accrued payroll and employee related expenses Legal And Related Services Current Legal and related services Carrying value as of the balance sheet date of obligations incurred through that date and payable for legal and related services. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Deferred Tax Liabilities, Gross [Abstract] Deferred tax liabilities: Clinical Related Expenses Current Clinical related Carrying value as of the balance sheet date of obligations incurred through that date and payable for clinical and related services. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Manufacturing Related Expenses Current Manufacturing related Carrying value as of the balance sheet date of obligations incurred through that date and payable for manufacturing of the entity's goods and services. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Deferred Tax Liabilities, Depreciation And Amortization Depreciation and amortization Amount of deferred tax liability attributable to taxable temporary differences depreciation and amortization. Deferred Tax Assets, Net Net Deferred tax assets (liabilities) Accrued Rent, Current Deferred rent Other Accrued Liabilities, Current Accrued other National Cancer Institute [Member] Agreement Term It represents the term of agreement. Cooperative Research and Development Agreement [Member] New Accounting Pronouncements, Policy [Policy Text Block] Recent Accounting Pronouncements Segment Reporting, Policy [Policy Text Block] Segment reporting Subsequent Events, Policy [Policy Text Block] Subsequent Events Reclassification, Policy [Policy Text Block] Reclassifications PolyBioCept, AB - Exclusive and Co-Exclusive License Agreement [Member] Property, Plant and Equipment, Estimated Useful Lives Chief Executive Officer [Member] Operating Loss Carryforwards Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount Operating Loss Carryforwards, Commencement Year Commencement year of each operating loss carryforward included in operating loss carryforward, in CCYY format. Operating Loss Carryforwards, Expiration Year Expiration year of each operating loss carryforward included in operating loss carryforward, in CCYY format. Document Information [Line Items] First Anniversary [Member] Satisfaction Of Clinical Trial Milestones [Member] Equal Monthly Installments [Member] Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Blank Check [Member] Income Tax Contingency [Line Items] Income Tax Authority [Domain] State and Local Jurisdiction [Member] Leasehold Improvements Paid by Landlord Acquisitions of property, plant and equipment under accounts payable Future cash outflow to pay for leasehold improvements that have occurred. Litigation Settlement, Payments for Penalties The amount of penalties paid in legal settlements during the reporting period. Manufacturing and Services Agreement, Amount Payable It Represent Manufacturing and Services Agreement, Amount Payable for the rreporting period. WuXi Apptech, Inc - Manufacturing and Services Agreement [Member] Manufacturing Suites [Member] Commercial Manufacturing cGMP Suite [Member] Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Federal Income Tax Expense (Benefit), Continuing Operations [Abstract] Federal: Current Federal Tax Expense (Benefit) Current Deferred Federal Income Tax Expense (Benefit) Deferred State and Local Income Tax Expense (Benefit), Continuing Operations [Abstract] State and Local Current State and Local Tax Expense (Benefit) Current Deferred State and Local Income Tax Expense (Benefit) Deferred Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount Change in Valuation Allowance Income Tax Expense (Benefit) Total income tax expense (benefit) Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Valuation allowance Effective Income Tax Rate Reconciliation, Percent, Total Effective tax rate