99900 - Disclosure - Standard And Custom Axis Domain Defaults link:presentationLink link:calculationLink link:definitionLink 00100 - Statement - Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 00200 - Statement - Consolidated Statements of Operations link:presentationLink link:calculationLink link:definitionLink 00300 - Statement - Consolidated Statements of Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 00500 - Statement - Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 40201 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Cash, Cash equivalents and Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 40302 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS - Available for sale debt securities (Details) link:presentationLink link:calculationLink link:definitionLink 40601 - Disclosure - INVENTORY (Details) link:presentationLink link:calculationLink link:definitionLink 40801 - Disclosure - PROPERTY AND EQUIPMENT, NET - (Details) link:presentationLink link:calculationLink link:definitionLink 40901 - Disclosure - ACCRUED EXPENSES (Details) link:presentationLink link:calculationLink link:definitionLink 41201 - Disclosure - INCOME TAXES - Net deferred tax assets and liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 41202 - Disclosure - INCOME TAXES - Reconciliation of the effective income tax rate (Details) link:presentationLink link:calculationLink link:definitionLink 41402 - Disclosure - LEASES - Right-of-use asset and lease liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 41403 - Disclosure - LEASES - Components of lease expenses (Details) link:presentationLink link:calculationLink link:definitionLink 41404 - Disclosure - LEASES - Maturities of the Company's operating lease liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 41404 - Disclosure - Maturities of the Company's operating lease liabilities (Details) (Calc 2) link:presentationLink link:calculationLink link:definitionLink 00090 - Document - Document And Entity Information link:presentationLink link:calculationLink link:definitionLink 00105 - Statement - Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 00400 - Statement - Consolidated Statements of Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 40101 - Disclosure - GENERAL ORGANIZATION, BUSINESS AND LIQUIDITY (Details) link:presentationLink link:calculationLink link:definitionLink 40202 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING PRACTICES - Useful lives, impairment (Details) link:presentationLink link:calculationLink link:definitionLink 40203 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Segment Reporting (Details) link:presentationLink link:calculationLink link:definitionLink 40204 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Net Loss per Share (Details) link:presentationLink link:calculationLink link:definitionLink 40301 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS - Cost and fair value (Details) link:presentationLink link:calculationLink link:definitionLink 40303 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 40304 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS - Fair value of company's financial assets (Details) link:presentationLink link:calculationLink link:definitionLink 40401 - Disclosure - PROLEUKIN ACQUISITION - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 40402 - Disclosure - PROLEUKIN ACQUISITION - Cash consideration and allocated fair value of assets acquired and liability assumed (Details) link:presentationLink link:calculationLink link:definitionLink 40403 - Disclosure - PROLEUKIN ACQUISITION - Additional information (Details) link:presentationLink link:calculationLink link:definitionLink 40501 - Disclosure - INTANGIBLE ASSETS, NET (Details) link:presentationLink link:calculationLink link:definitionLink 40701 - Disclosure - REVENUE (Details) link:presentationLink link:calculationLink link:definitionLink 40802 - Disclosure - PROPERTY AND EQUIPMENT, NET - Other information (Details) link:presentationLink link:calculationLink link:definitionLink 41001 - Disclosure - STOCKHOLDERS' EQUITY (Details) link:presentationLink link:calculationLink link:definitionLink 41002 - Disclosure - STOCKHOLDERS' EQUITY - Stock Options (Details) link:presentationLink link:calculationLink link:definitionLink 41003 - Disclosure - STOCKHOLDERS' EQUITY - Restricted Stock Units and Performance Restricted Stock Units (Details) link:presentationLink link:calculationLink link:definitionLink 41004 - Disclosure - STOCKHOLDERS' EQUITY - Stock based expense (Details) link:presentationLink link:calculationLink link:definitionLink 41005 - Disclosure - STOCKHOLDERS' EQUITY - Stock-based compensation by instrument (Details) link:presentationLink link:calculationLink link:definitionLink 41006 - Disclosure - STOCKHOLDERS' EQUITY - Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 41101 - Disclosure - EMPLOYEE BENEFIT PLAN (Details) link:presentationLink link:calculationLink link:definitionLink 41203 - Disclosure - INCOME TAXES - Other information (Details) link:presentationLink link:calculationLink link:definitionLink 41204 - Disclosure - INCOME TAXES - Unrecognized benefits (Details) link:presentationLink link:calculationLink link:definitionLink 41301 - Disclosure - LICENSES AND AGREEMENTS (Details) link:presentationLink link:calculationLink link:definitionLink 41302 - Disclosure - LICENSES AND AGREEMENTS - Estimated purchase obligations (Details) link:presentationLink link:calculationLink link:definitionLink 41401 - Disclosure - LEASES - Additional information (Details) link:presentationLink link:calculationLink link:definitionLink 41501 - Disclosure - LEGAL PROCEEDINGS (Details) link:presentationLink link:calculationLink link:definitionLink 41601 - Disclosure - LONG-TERM NOTE PAYABLE (Details) link:presentationLink link:calculationLink link:definitionLink 41701 - Disclosure - SUBSEQUENT EVENTS (Details) link:presentationLink link:calculationLink link:definitionLink 10101 - Disclosure - GENERAL ORGANIZATION, BUSINESS AND LIQUIDITY link:presentationLink link:calculationLink link:definitionLink 10201 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES link:presentationLink link:calculationLink link:definitionLink 10301 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS link:presentationLink link:calculationLink link:definitionLink 10401 - Disclosure - PROLEUKIN ACQUISITION link:presentationLink link:calculationLink link:definitionLink 10501 - Disclosure - INTANGIBLE ASSETS, NET link:presentationLink link:calculationLink link:definitionLink 10601 - Disclosure - INVENTORY link:presentationLink link:calculationLink link:definitionLink 10701 - Disclosure - REVENUE link:presentationLink link:calculationLink link:definitionLink 10801 - Disclosure - PROPERTY AND EQUIPMENT, NET link:presentationLink link:calculationLink link:definitionLink 10901 - Disclosure - ACCRUED EXPENSES link:presentationLink link:calculationLink link:definitionLink 11001 - Disclosure - STOCKHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 11101 - Disclosure - EMPLOYEE BENEFIT PLAN link:presentationLink link:calculationLink link:definitionLink 11201 - Disclosure - INCOME TAXES link:presentationLink link:calculationLink link:definitionLink 11301 - Disclosure - LICENSES AND AGREEMENTS link:presentationLink link:calculationLink link:definitionLink 11401 - Disclosure - LEASES link:presentationLink link:calculationLink link:definitionLink 11501 - Disclosure - LEGAL PROCEEDINGS link:presentationLink link:calculationLink link:definitionLink 11601 - Disclosure - LONG-TERM NOTE PAYABLE link:presentationLink link:calculationLink link:definitionLink 11701 - Disclosure - SUBSEQUENT EVENTS link:presentationLink link:calculationLink link:definitionLink 20202 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Policies) link:presentationLink link:calculationLink link:definitionLink 30203 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables) link:presentationLink link:calculationLink link:definitionLink 30303 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS (Tables) link:presentationLink link:calculationLink link:definitionLink 30403 - Disclosure - PROLEUKIN ACQUISITION (Tables) link:presentationLink link:calculationLink link:definitionLink 30503 - Disclosure - INTANGIBLE ASSETS, NET (Tables) link:presentationLink link:calculationLink link:definitionLink 30603 - Disclosure - INVENTORY (Tables) link:presentationLink link:calculationLink link:definitionLink 30803 - Disclosure - PROPERTY AND EQUIPMENT, NET (Tables) link:presentationLink link:calculationLink link:definitionLink 30903 - Disclosure - ACCRUED EXPENSES (Tables) link:presentationLink link:calculationLink link:definitionLink 31003 - Disclosure - STOCKHOLDERS' EQUITY (Tables) link:presentationLink link:calculationLink link:definitionLink 31203 - Disclosure - INCOME TAXES (Tables) link:presentationLink link:calculationLink link:definitionLink 31403 - Disclosure - LEASES (Tables) link:presentationLink link:calculationLink link:definitionLink 41205 - Disclosure - INCOME TAXES (Details) link:presentationLink link:calculationLink link:definitionLink