99900 - Disclosure - Standard And Custom Axis Domain Defaults link:presentationLink link:calculationLink link:definitionLink 995200100 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 995200200 - Statement - Condensed Consolidated Statements of Operations link:presentationLink link:calculationLink link:definitionLink 995200300 - Statement - Condensed Consolidated Statements of Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 995200500 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 99940201 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Cash, Cash equivalents and Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 99940302 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS - Available for sale debt securities (Details) link:presentationLink link:calculationLink link:definitionLink 99940401 - Disclosure - INTANGIBLE ASSETS, NET (Details) link:presentationLink link:calculationLink link:definitionLink 99940501 - Disclosure - INVENTORY (Details) link:presentationLink link:calculationLink link:definitionLink 99940602 - Disclosure - REVENUE - GTN Adjustments (Details) link:presentationLink link:calculationLink link:definitionLink 99940701 - Disclosure - PROPERTY AND EQUIPMENT, NET - (Details) link:presentationLink link:calculationLink link:definitionLink 99940801 - Disclosure - ACCRUED EXPENSES (Details) link:presentationLink link:calculationLink link:definitionLink 99941001 - Disclosure - SEGMENT INFORMATION (Details) link:presentationLink link:calculationLink link:definitionLink 99941202 - Disclosure - LEASES - Right-of-use asset and lease liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 99941203 - Disclosure - LEASES - Components of lease expenses (Details) link:presentationLink link:calculationLink link:definitionLink 99941204 - Disclosure - LEASES - Maturities of the Company's operating lease liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 41604 - Disclosure - LEASES - Maturities of the Company's operating lease liabilities (Details) (Calc 2) link:presentationLink link:calculationLink link:definitionLink 995200090 - Document - Document And Entity Information link:presentationLink link:calculationLink link:definitionLink 995200105 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 995200400 - Statement - Condensed Consolidated Statements of Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 99940101 - Disclosure - GENERAL ORGANIZATION, BUSINESS AND LIQUIDITY (Details) link:presentationLink link:calculationLink link:definitionLink 99940202 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Net Loss per Share (Details) link:presentationLink link:calculationLink link:definitionLink 99940203 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Income taxes & Segment Reporting (Details) link:presentationLink link:calculationLink link:definitionLink 99940301 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS - Cost and fair value (Details) link:presentationLink link:calculationLink link:definitionLink 99940303 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 99940304 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS - Fair value of company's financial assets (Details) link:presentationLink link:calculationLink link:definitionLink 99940402 - Disclosure - INTANGIBLE ASSETS, NET - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 99940601 - Disclosure - REVENUE (Details) link:presentationLink link:calculationLink link:definitionLink 99940603 - Disclosure - REVENUE - Consolidated net product revenue by geographic area (Details) link:presentationLink link:calculationLink link:definitionLink 99940604 - Disclosure - REVENUE - Concentration (Details) link:presentationLink link:calculationLink link:definitionLink 99940901 - Disclosure - STOCKHOLDERS' EQUITY (Details) link:presentationLink link:calculationLink link:definitionLink 99940902 - Disclosure - STOCKHOLDERS' EQUITY - Stock Options (Details) link:presentationLink link:calculationLink link:definitionLink 99940903 - Disclosure - STOCKHOLDERS' EQUITY - Restricted Stock Units and Performance Restricted Stock Units (Details) link:presentationLink link:calculationLink link:definitionLink 99940904 - Disclosure - STOCKHOLDERS' EQUITY - Stock-based compensation by instrument (Details) link:presentationLink link:calculationLink link:definitionLink 99941101 - Disclosure - LICENSES AND AGREEMENTS (Details) link:presentationLink link:calculationLink link:definitionLink 99941102 - Disclosure - LICENSES AND AGREEMENTS - Estimated purchase obligations (Details) link:presentationLink link:calculationLink link:definitionLink 99941201 - Disclosure - LEASES - Additional information (Details) link:presentationLink link:calculationLink link:definitionLink 99941301 - Disclosure - LEGAL PROCEEDINGS (Details) link:presentationLink link:calculationLink link:definitionLink 995210101 - Disclosure - GENERAL ORGANIZATION, BUSINESS AND LIQUIDITY link:presentationLink link:calculationLink link:definitionLink 995210201 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES link:presentationLink link:calculationLink link:definitionLink 995210301 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS link:presentationLink link:calculationLink link:definitionLink 995210401 - Disclosure - INTANGIBLE ASSETS, NET link:presentationLink link:calculationLink link:definitionLink 995210501 - Disclosure - INVENTORY link:presentationLink link:calculationLink link:definitionLink 995210601 - Disclosure - REVENUE link:presentationLink link:calculationLink link:definitionLink 995210701 - Disclosure - PROPERTY AND EQUIPMENT, NET link:presentationLink link:calculationLink link:definitionLink 995210801 - Disclosure - ACCRUED EXPENSES link:presentationLink link:calculationLink link:definitionLink 995210901 - Disclosure - STOCKHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 995211001 - Disclosure - SEGMENT INFORMATION link:presentationLink link:calculationLink link:definitionLink 995211101 - Disclosure - LICENSES AND AGREEMENTS link:presentationLink link:calculationLink link:definitionLink 995211201 - Disclosure - LEASES link:presentationLink link:calculationLink link:definitionLink 995211301 - Disclosure - LEGAL PROCEEDINGS link:presentationLink link:calculationLink link:definitionLink 995211401 - Disclosure - INCOME TAXES link:presentationLink link:calculationLink link:definitionLink 99920202 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Policies) link:presentationLink link:calculationLink link:definitionLink 99930203 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables) link:presentationLink link:calculationLink link:definitionLink 99930303 - Disclosure - CASH EQUIVALENTS AND INVESTMENTS (Tables) link:presentationLink link:calculationLink link:definitionLink 99930403 - Disclosure - INTANGIBLE ASSETS, NET (Tables) link:presentationLink link:calculationLink link:definitionLink 99930503 - Disclosure - INVENTORY (Tables) link:presentationLink link:calculationLink link:definitionLink 99930603 - Disclosure - REVENUE (Tables) link:presentationLink link:calculationLink link:definitionLink 99930703 - Disclosure - PROPERTY AND EQUIPMENT, NET (Tables) link:presentationLink link:calculationLink link:definitionLink 99930803 - Disclosure - ACCRUED EXPENSES (Tables) link:presentationLink link:calculationLink link:definitionLink 99930903 - Disclosure - STOCKHOLDERS' EQUITY (Tables) link:presentationLink link:calculationLink link:definitionLink 99931003 - Disclosure - SEGMENT INFORMATION (Tables) link:presentationLink link:calculationLink link:definitionLink 99931203 - Disclosure - LEASES (Tables) link:presentationLink link:calculationLink link:definitionLink 99941401 - Disclosure - INCOME TAXES (Details) link:presentationLink link:calculationLink link:definitionLink